Drug discovery and DNA-based research

From gene to molecule, with a citation on every number.

Pharmint Discover brings target biology, chemistry, structures, genetics and literature into one workspace. It is built entirely on permissively licensed public data, so every value on the screen can be traced back to the record it came from.

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Data licensing cost: Zero
Public sources: 20
Values without a source: None

Abstract blue and white organic molecular structure

Logan Voss / Unsplash

One workspace for the whole question

Start from a disease, a gene, a variant, a protein or a molecule. Each page is assembled from the same underlying records and links onward to the next.

Linked spheres illustrating a molecular network

Target dossiers

Disease associations, genetic evidence, tractability, safety, expression and known drugs for any gene or protein, from Open Targets and UniProt.

Molecular structure with glowing blue nodes

Molecule profiles

Structure, physicochemical properties, drug-likeness, ADMET predictions, measured bioactivity and similar compounds across ChEMBL, PubChem and BindingDB.

Virtual screening

Dock a ligand set against an experimental or predicted structure with AutoDock Vina and review ranked poses in the browser.

Genetics and variants

Follow a variant to its gene, its clinical significance and the targets it implicates, with ClinVar and GWAS Catalog evidence.

Sequence toolbox

Translate, find ORFs, search Swiss-Prot and NCBI, design primers and score CRISPR guides against GRCh38.

Two researchers in lab coats working in a laboratory

Research assistant

Ask questions in plain language. The assistant queries the same data as every page and cites the record behind each answer.

Built to be checked

The platform is validated by working pharmaceutical scientists. Their tools for doing that are part of the product, not an afterthought.

A citation on every value

Each number links to the dataset, release and record it came from, so a claim can be checked in seconds.

Flag anything

Mark a value as correct, incorrect or questionable with a note. Flags land in a review queue and are answered.

Shared workspaces

Save targets, molecules and screens into projects shared with collaborators, with comments alongside the evidence.

A scientist in a white lab coat using a laptop in a laboratory

ThisisEngineering / Unsplash

Open data, used as licensed

Every dataset is public and commercially usable. Sources that carry attribution or share-alike terms are marked and handled accordingly. Gated databases are not used.

Full attribution and licenses

Indexed on the platform

Open Targets PlatformTarget-disease associations, genetic evidence, tractability and safety.
CC0 1.0
UniProt (Swiss-Prot)Reviewed protein sequences, function and annotation.
CC BY 4.0
ChEMBLCurated bioactivity, compound-target relationships and ADMET annotations.
CC BY-SA 3.0
PubChemCompound structures, names, synonyms and identifiers.
Public domain
BindingDBMeasured protein-ligand binding affinities (Ki, IC50, Kd).
CC BY 3.0 (curated rows)
ZINC20In-stock, drug-like screening compounds.
Free to use
Tox21 / ToxCastQuantitative high-throughput toxicity assays.
US public domain
AlphaFold Protein Structure DatabasePredicted structures with per-residue confidence.
CC BY 4.0
ClinVarVariant-disease and drug-response classifications.
US public domain
GWAS CatalogCurated variant-trait associations.
EMBL-EBI terms of use
GTEx (open tier)Median gene expression per tissue.
GTEx open-access data
Human Protein AtlasProtein expression across tissues, cells and pathology.
CC BY-SA 4.0

Queried live

RCSB Protein Data BankExperimental macromolecular structures.
CC0 1.0
ClinicalTrials.govRegistry and results of human studies.
US public domain
openFDA / FDA Orange BookApproved drugs, labels, adverse events.
US public domain / CC0
Europe PMCBiomedical literature abstracts and open-access full text.
Mixed; abstracts per publisher terms
NCBI BLASTRemote nucleotide similarity search against nt/nr.
US public domain

Scientists in lab coats working with test tubes

Vitaly Gariev / Unsplash

Request access

Access is by invitation while the platform is validated. Tell us who you are and what you are working on; an administrator will send an invite link.